Bivalirudin Pharmacology 

Bivalirudin
Bivalirudin
Anticoagulant,Thrombin inhibitor.
Anticoagulant,Thrombin inhibitor.
Inhibits the action of thrombin by binding both to its catalytic site and to its anion-binding exosite of circulating
and clot-bound thrombin.
Inhibits the action of thrombin by binding both to its catalytic site and to its anion-binding exosite of circulating
and clot-bound thrombin.
Absorption: It is not absorbed orally; Should be given parenterally.
Dstribution: drug distribution is limited to the intravascular compartment. Bivalirudin does not bind to plasma proteins, other than thrombin, or to red blood cells.
Metabolism: Metabolism of bivalirudin occurs in the liver or by other sites by means of proteolysis.
Excretion: Excreted as fragments in urine.
Absorption: It is not absorbed orally; Should be given parenterally.
Dstribution: drug distribution is limited to the intravascular compartment. Bivalirudin does not bind to plasma proteins, other than thrombin, or to red blood cells.
Metabolism: Metabolism of bivalirudin occurs in the liver or by other sites by means of proteolysis.
Excretion: Excreted as fragments in urine.
Absorption: It is not absorbed orally; Should be given parenterally.
Dstribution: drug distribution is limited to the intravascular compartment. Bivalirudin does not bind to plasma proteins, other than thrombin, or to red blood cells.
Metabolism: Metabolism of bivalirudin occurs in the liver or by other sites by means of proteolysis.
Excretion: Excreted as fragments in urine.
Absorption: It is not absorbed orally; Should be given parenterally.
Dstribution: drug distribution is limited to the intravascular compartment. Bivalirudin does not bind to plasma proteins, other than thrombin, or to red blood cells.
Metabolism: Metabolism of bivalirudin occurs in the liver or by other sites by means of proteolysis.
Excretion: Excreted as fragments in urine.
40 minutes after infusion
40 minutes after infusion
25 ? 210 minutes
25 ? 210 minutes
1.Bleeding 2.Hypersensitivity reactions 3.Cardiac problem 4.Nausea
5.Vomiting 6.Dyspepsia 7.Headache
Inj site pain and Anxiety
Potentially Fatal: Severe anaphylactic reactions which may lead to death
1.Bleeding 2.Hypersensitivity reactions 3.Cardiac problem 4.Nausea
5.Vomiting 6.Dyspepsia 7.Headache
Inj site pain and Anxiety
Potentially Fatal: Severe anaphylactic reactions which may lead to death
Cerebral aneurysm
Hypersensitivity to bivalirudin or its components 3.Intracranial hemorrhage
General uncontrollable hemorrhage
Active major bleeding
Cerebral aneurysm
Hypersensitivity to bivalirudin or its components 3.Intracranial hemorrhage
General uncontrollable hemorrhage
Active major bleeding
1.Serious bleeding 2.Hepatic impairment
3.Renal impairment
1.Serious bleeding 2.Hepatic impairment
3.Renal impairment
Use with caution
Use with caution


One thought on “Bivalirudin Pharmacology

  1. I have been browsing online more than three hours today yet I never found any interesting article like yours It is pretty worth enough for me In my view if all website owners and bloggers made good content as you did the internet will be a lot more useful than ever before.

Leave a Reply

Your email address will not be published. Required fields are marked *

en English
Enable Notifications OK No thanks