Betaxolol Pharmacology 

Betaxolol
Betaxolol
Cardioselective Beta 1-adrenergic blocker, anti glaucoma, antihypertensive.
Cardioselective Beta 1-adrenergic blocker, anti glaucoma, antihypertensive.
Betaxolol is a selective beta 1 (? 1) blocker. It inhibits the beta receptors present in the eye such as in the ciliary body epithelium and blood vessels. This will leads to decreased aqueous production and reduced intraocular pressure. Aqueous humor production is activated by ? receptor mediated cyclic AMP phosphokinase pathway. Beta receptor blockers will decreases the intracellular cyclic AMP level and reduces intraocular pressure. It is less efficacious than non selective ? blocker since most of the ? receptors in the eye are of (?2) sub type.
Betaxolol is a selective beta 1 (? 1) blocker. It inhibits the beta receptors present in the eye such as in the ciliary body epithelium and blood vessels. This will leads to decreased aqueous production and reduced intraocular pressure. Aqueous humor production is activated by ? receptor mediated cyclic AMP phosphokinase pathway. Beta receptor blockers will decreases the intracellular cyclic AMP level and reduces intraocular pressure. It is less efficacious than non selective ? blocker since most of the ? receptors in the eye are of (?2) sub type.
Absorption: Absorption of the drug after ophthalmic use is minimal.
Absorption: Absorption of the drug after ophthalmic use is minimal.
Absorption: Absorption of the drug after ophthalmic use is minimal.
Absorption: Absorption of the drug after ophthalmic use is minimal.
12- 24 hours
12- 24 hours
N/A
N/A
1.Irritation 2.Burning 3.Photophobia 4.Erythema 5.Itching 6.Keratitis
7.Tearing
1.Irritation 2.Burning 3.Photophobia 4.Erythema 5.Itching 6.Keratitis
7.Tearing
1.Hypersensitivity to Betaxolol 2.Bradycardia
3.Heart failure 4.Cardiogenic shock
5.Heart block (2nd or 3rd degree)
1.Hypersensitivity to Betaxolol 2.Bradycardia
3.Heart failure 4.Cardiogenic shock
5.Heart block (2nd or 3rd degree)
Diabetes
Angle closure glaucoma
Chronic obstructive pulmonary diseases 4.Bronchial asthma
Thyrotoxicosis
General anaesthesia
Diabetes
Angle closure glaucoma
Chronic obstructive pulmonary diseases 4.Bronchial asthma
Thyrotoxicosis
General anaesthesia
Use with caution
Use with caution
Use with caution
Use with caution
Use with caution
Use with caution
Contraindicated
Contraindicated