Benzocaine Pharmacology 

Benzocaine
Benzocaine
Ester Local Anesthetic
Ester Local Anesthetic
It binds to sodium channel and reversibly stabilizes the neuronal membrane which decreases its permeability to sodium ions. This results the blocking of depolarization of the neuronal membrane and initiation and conduction
of nerve impulses at the site where it applies.
It binds to sodium channel and reversibly stabilizes the neuronal membrane which decreases its permeability to sodium ions. This results the blocking of depolarization of the neuronal membrane and initiation and conduction
of nerve impulses at the site where it applies.
Absorption- It is poorly absorbed from the intact epidermis.
Absorption- It is poorly absorbed from the intact epidermis.
Absorption- It is poorly absorbed from the intact epidermis.
Absorption- It is poorly absorbed from the intact epidermis.
5 to 45 minutes
5 to 45 minutes
N/A
N/A
Urticaria.
Burning.
Stinging.
Tenderness.
Irritation.
Itching.
Erythema.
Rash.
Edema
Urticaria.
Burning.
Stinging.
Tenderness.
Irritation.
Itching.
Erythema.
Rash.
Edema
Contraindicated in patients with hypersensitivity to the drug
Contraindicated in patients with hypersensitivity to the drug
G6PD deficiency.
Traumatized mucus.
Local sepsis.
G6PD deficiency.
Traumatized mucus.
Local sepsis.
Use with caution
Use with caution
Use with caution
Use with caution
Use with caution
Use with caution
Use with caution
Below 2 years – Contraindicated
Use with caution
Below 2 years – Contraindicated
Local anaesthetic agent
Topical Analgesics
Local anaesthetic agent
Topical Analgesics
N/A
N/A
Topical-
Dental pain and dental procedures-
Adults and children- 20% gel or paste to area whenever necessary Pruritic conditions-
Adult- 1%- 20% topical preparation to the affected area 3 to 4 times daily Otitis media and other forms of otitis-
Adults- 4 to 5 drops in external auditory canal; repeat every 1 to 2 hour Sore throat pain-
Adults and children (>3 years) – 3:1 lozenge whenever necessary Slowly dissolved in the mouth
Male genital desensitization-
Adults- 3 to 7.5 % (water soluble base) topical preparations Apply on head and shaft of penis before intercourse
Topical-
Dental pain and dental procedures-
Adults and children- 20% gel or paste to area whenever necessary Pruritic conditions-
Adult- 1%- 20% topical preparation to the affected area 3 to 4 times daily Otitis media and other forms of otitis-
Adults- 4 to 5 drops in external auditory canal; repeat every 1 to 2 hour Sore throat pain-
Adults and children (>3 years) – 3:1 lozenge whenever necessary Slowly dissolved in the mouth
Male genital desensitization-
Adults- 3 to 7.5 % (water soluble base) topical preparations Apply on head and shaft of penis before intercourse
N/A
N/A
Store at room temperature, away from heat and direct light. Keep out of the reach of children.
Store at room temperature, away from heat and direct light. Keep out of the reach of children.
Apply the missed dose as soon as noticed and if it is the time for next dose then skip the missed dose. Continue
the regular schedule. Do not double the dose.
Apply the missed dose as soon as noticed and if it is the time for next dose then skip the missed dose. Continue
the regular schedule. Do not double the dose.