| Bacitracin Pharmacology |
| Bacitracin |
| About Bacitracin |
| Polypeptide antibiotic. |
| Mechanism of Action of Bacitracin |
| Bacitracin is an antibiotic produced by the strain of Bacillus subtilis. It acts by inhibiting bacterial cell wall
synthesis. It is active against a variety of gram positive and a few gram negative organisms. |
| Pharmacokinets of Bacitracin |
| N/A |
| Onset of Action for Bacitracin |
| N/A |
| Duration of Action for Bacitracin |
| N/A |
| Half Life of Bacitracin |
| N/A |
| Side Effects of Bacitracin |
| 1.Albuminuria 2.Cylindruria 3.Azotemia
4.Rising blood levels without any increase in dosage. 5.Nausea
|
| Contra-indications of Bacitracin |
| Hypersensitivity to the drug |
| Special Precautions while taking Bacitracin |
| Hypersensitivity to other antibiotics |
| Pregnancy Related Information |
| Use with caution |
| Old Age Related Information |
| Use with caution |
| Breast Feeding Related Information |
| Use with caution |
| Children Related Information |
| Use with caution |
| Indications for Bacitracin |
| Locally used for secondarily infected wounds, ulcers, pyodermas and other superficial skin infections. In the eye: Superficial infections of the eye
Nasal application: Bacitracin-susceptible infections of the upper and lower respiratory tract IM: Pneumonia and empyema caused by staphylococci in infants |
| Interactions for Bacitracin |
| N/A |
| Typical Dosage for Bacitracin |
| Infants:IM use
For infants under 2.5kg: 900 units/kg/day in 2 or 3 divided doses. For infants over 2.5kg:1000 units/kg/day in 2 or 3 divided doses. Local use: Apply locally once or twice daily in the affected area |
| Schedule of Bacitracin |
| N/A |
| Storage Requirements for Bacitracin |
| Parenteral preapration: Stored at 2 – 8 degree Celsius.Other preaparations should be stored at 15 – 30 degree
Celsius |
| Effects of Missed Dosage of Bacitracin |
| Apply the missed dose as soon as noticed and if it is the time for next dose then skip the missed dose. Continue
the regular schedule. Do not double the dose. |
| Effects of Overdose of Bacitracin |
| Give supportive measures and symptomatic treatment. |