Amorolfine Pharmacology |
Amorolfine |
About Amorolfine |
An allylamine derivative,Squalene monooxygenase inhibitor, Antifungal. |
Mechanism of Action of Amorolfine |
It is fungistatic or fungicidal depnding on the drug concentration. It inhibits the sterol biosynthesis which is an important constituent of cell membrane of fungus |
Pharmacokinets of Amorolfine |
Absorption: Amorolfine from nail lacquer penetrates and diffuses through the nail plate. |
Onset of Action for Amorolfine |
N/A |
Duration of Action for Amorolfine |
N/A |
Half Life of Amorolfine |
N/A |
Side Effects of Amorolfine |
1.Redness 2.Itching 3.Burning sensation 4.Pruritus 5.Vesicles 6.Periungual scaling 7.Nail discolouration |
Contra-indications of Amorolfine |
Hypersensitivity to Amorolfine |
Special Precautions while taking Amorolfine |
N/A |
Pregnancy Related Information |
Contraindicated |
Old Age Related Information |
Use with caution |
Breast Feeding Related Information |
Contraindicated |
Children Related Information |
Contraindicated |
Indications for Amorolfine |
Onychomycosis |
Interactions for Amorolfine |
N/A |
Typical Dosage for Amorolfine |
Apply the nail lacquer to the affected finger or toenails once or twice a week, after filing and cleaning the nails. |
Schedule of Amorolfine |
N/A |
Storage Requirements for Amorolfine |
Store below 30?C. Keep out of reach of children. |
Effects of Missed Dosage of Amorolfine |
Apply the missed dose as soon as noticed and if it is the times for next dose skip the missed dose. Continue the regular schedule. Do not double the dose |
Effects of Overdose of Amorolfine |
Give supportive measures and symptomatic treatment. |