| Aminobenzoic acid Pharmacology |
| Aminobenzoic acid |
| About Aminobenzoic acid |
| UVB filter agent, a component of folic acid, An antioxidant (Sunscreen). |
| Mechanism of Action of Aminobenzoic acid |
| Aminobenzoic acid is commonly known as Para-amino benzoic acid.Para-amino benzoic acid (PABA) is a sunscreen that prevents sunburn and protects skin from the harmful effects of the sun. It is a chemical sunscreen which absorbs ultraviolet (UV) and visible sun light. Limiting exposure to the sun and using sunscreen agents can help prevent early wrinkling and skin cancer. Para-amino benzoic acid is only available in combination with other sunscreen agents. Sunscreens absorb, reflect, or scatter radiation in the UV range at wavelengths of 290 to 400 nanometers. UVA radiation is at wavelengths 360-400 nanometers and UVB radiation is at wavelengths 290-320 nanometers. PABA absorbs UVB radiations. |
| Pharmacokinets of Aminobenzoic acid |
| Absorption: Amino benzoic acid is applied topically to the skin. Penetration of PABA into the skin from the sunscreen product depends on the solvent used in the formulation. Alcohol solvents allow for the most rapid and deepest epidermal penetration of sunscreens. It does not enter in to the systemic circulation. |
| Onset of Action for Aminobenzoic acid |
| N/A |
| Duration of Action for Aminobenzoic acid |
| N/A |
| Half Life of Aminobenzoic acid |
| N/A |
| Side Effects of Aminobenzoic acid |
| 1. Dry skin 2. Burning 3. Redness 4. Rashes 5. Itching 6. Swelling 7. Acne 8. Irritation 9. Painful, red, pus-filled blisters in hair follicles 10. Pain in hairy areas |
| Contra-indications of Aminobenzoic acid |
| 1. Hypersensitivity to Amino benzoic acid 2. Irritated or broken skin. |
| Special Precautions while taking Aminobenzoic acid |
| 1. Avoid contact with the eyes and mouth 2. For external use only |
| Pregnancy Related Information |
| Use with caution |
| Old Age Related Information |
| Use with caution |
| Breast Feeding Related Information |
| Use with caution |
| Children Related Information |
| Use with caution NEONATES : Contraindicated |
| Indications for Aminobenzoic acid |
| 1. Fade dark skin spot- freckles, age spots 2. Drug induced phototoxicity 3. Adjunct in Vitiligo therapy |
| Interactions for Aminobenzoic acid |
| N/A |
| Typical Dosage for Aminobenzoic acid |
| Topical: Apply the medicament as thin film on the affected area with gentle massage half an hour before exposure to sunlight. |
| Schedule of Aminobenzoic acid |
| C1 |
| Storage Requirements for Aminobenzoic acid |
| Store in a cool, dry place away from heat and direct sunlight. Keep out of the reach of children. |
| Effects of Missed Dosage of Aminobenzoic acid |
| Apply the missed dose as soon as noticed and if it is the time for next dose then skip the missed dose. Continue the regular schedule. Do not double the dose. |
| Effects of Overdose of Aminobenzoic acid |
| Give supportive measures and symptomatic treatment. |