Bisacodyl Pharmacology 

Bisacodyl
Bisacodyl
Diphenyl methane derivative ,Stimulant (irritant)Laxative
Diphenyl methane derivative ,Stimulant (irritant)Laxative
Bisacodyl is a stimulant (irritant) laxative. It acts directly on the colonic mucosa-where it stimulates sensory nerve endings in the walls of the intestine and the rectum to produce parasympathetic reflexes resulting in
increased peristaltic contractions of the colon and cause defecation.
Bisacodyl is a stimulant (irritant) laxative. It acts directly on the colonic mucosa-where it stimulates sensory nerve endings in the walls of the intestine and the rectum to produce parasympathetic reflexes resulting in
increased peristaltic contractions of the colon and cause defecation.
Absorption: 5% of the drug is absorbed after oral administration.Distribution: It is distributed locally.
Metabolism: It is hydrolyzed by intestinal enzymes esterases and bacteria in the bowel to active desacetyl forms.Excretion: Bisacodyl is excreted mainly in the stool. Absorbed drug is excreted in urine.
Absorption: 5% of the drug is absorbed after oral administration.Distribution: It is distributed locally.
Metabolism: It is hydrolyzed by intestinal enzymes esterases and bacteria in the bowel to active desacetyl forms.Excretion: Bisacodyl is excreted mainly in the stool. Absorbed drug is excreted in urine.
Absorption: 5% of the drug is absorbed after oral administration.Distribution: It is distributed locally.
Metabolism: It is hydrolyzed by intestinal enzymes esterases and bacteria in the bowel to active desacetyl forms.Excretion: Bisacodyl is excreted mainly in the stool. Absorbed drug is excreted in urine.
Absorption: 5% of the drug is absorbed after oral administration.Distribution: It is distributed locally.
Metabolism: It is hydrolyzed by intestinal enzymes esterases and bacteria in the bowel to active desacetyl forms.Excretion: Bisacodyl is excreted mainly in the stool. Absorbed drug is excreted in urine.
N/A
N/A
N/A
N/A
1.Abdominal discomfort 2.Abdominal cramps 3.Diarrhea
4.Rectal irritation
1.Abdominal discomfort 2.Abdominal cramps 3.Diarrhea
4.Rectal irritation
1.Hypersensitivity to Bisacodyl 2.Intestinal obstruction
3.Obstruction of the intestines due to loss of intestinal movement 4.Severe dehydration
Sudden abdominal conditions requiring surgery (appendicitis)
Sudden attacks of inflammatory bowel disease (ulcerative colitis or Crohn`s disease) 7.Anal fissure
8.Ulcerative proctitis
1.Hypersensitivity to Bisacodyl 2.Intestinal obstruction
3.Obstruction of the intestines due to loss of intestinal movement 4.Severe dehydration
Sudden abdominal conditions requiring surgery (appendicitis)
Sudden attacks of inflammatory bowel disease (ulcerative colitis or Crohn`s disease) 7.Anal fissure
8.Ulcerative proctitis
1.Nausea 2.Vomiting 3.Abdominal pain
4.Prolong use
1.Nausea 2.Vomiting 3.Abdominal pain
4.Prolong use
Use with caution
Use with caution