| Bacillus Clausii Pharmacology |
| Bacillus Clausii |
| About Bacillus Clausii |
| Bacillus clausii is a rod-shaped, Gram-positive, motile and spore-forming bacterium which lives in the soil. It is
presently classified as probiotic. |
| Mechanism of Action of Bacillus Clausii |
| Bacillus clausii spores, normal inhabitants of the intestine, with no pathogenic powers. Administered orally, Bacillus clausii spores, due to their high-resistance to both chemical and physical agents, cross the barrier of the gastric juices reaching unharmed the intestinal tract where they are transformed into metabolically active vegetative cells.
The administration of Bacillus clausii contributes to the recovery of the intestinal microbial flora altered during the course of microbial disorders of diverse origin. Bacillus clausii is capable of producing various vitamins, in particular group B vitamins, hence it contributes to correcting the consequent vitamin disorders caused by antibiotics and chemotherapeutic agents in general. Bacillus clausii makes it possible to obtain a nonspecific antigenic and antitoxic action, closely connected with the metabolic action of clausii. In addition, the high degree of heterologous resistance to the antibiotics induced artificially, provides for the creation of the therapeutic basis for preventing the alteration of the intestinal microbial flora, following the selective action of antibiotics, especially the broad-spectrum ones or to re-establish its balance. Due to its antibiotic resistance, Bacillus clausii can be administered in the interval between 2 doses of antibiotic. The antibiotic-resistance refers to penicillin, cephalosporins, tetracyclines, macrolides, aminoglycosides, novobiocin, chloramphenicol, thiamphenicol, lincomycin, isoniazid, cycloserine, rifampicin, nalidixic acid and pipemidic acid. |
| Pharmacokinets of Bacillus Clausii |
| N/A |
| Onset of Action for Bacillus Clausii |
| N/A |
| Duration of Action for Bacillus Clausii |
| N/A |
| Half Life of Bacillus Clausii |
| N/A |
| Side Effects of Bacillus Clausii |
| N/A |
| Contra-indications of Bacillus Clausii |
| N/A |
| Special Precautions while taking Bacillus Clausii |
| During antibiotic therapy, Erceflora should be administered in the interval between 1 dose of antibiotic and the
next. |
| Pregnancy Related Information |
| May be used |
| Old Age Related Information |
| May be used |
| Breast Feeding Related Information |
| May be used |
| Children Related Information |
| May be used |
| Indications for Bacillus Clausii |
| 1.Acute diarrhea with duration of ?14 days due to infection, drugs or poisons. 2.Chronic or persistent diarrhea with duration of >14 days.
3.Treatment of alterations in the intestinal bacterial flora. |
| Interactions for Bacillus Clausii |
| N/A |
| Typical Dosage for Bacillus Clausii |
Administration at regular intervals (3-4 hrs), diluting the content of the vial in sweetened water, milk, tea or orange juice.
|
| Schedule of Bacillus Clausii |
| N/A |
| Storage Requirements for Bacillus Clausii |
| N/A |
| Effects of Missed Dosage of Bacillus Clausii |
| N/A |
| Effects of Overdose of Bacillus Clausii |
| N/A |