| Albumin Pharmacology |
| Albumin |
| About Albumin |
| I V Sterile solutions, Plasma expanders |
| Mechanism of Action of Albumin |
| Human albumin increases intravascular oncotic pressure and causes movement of fluids from interstitial into intravascular space. Absorption: Administered intravenously Metabolism: Metabolised in the body Excretion: Excreted through urine |
| Pharmacokinets of Albumin |
| N/A |
| Onset of Action for Albumin |
| N/A |
| Duration of Action for Albumin |
| N/A |
| Half Life of Albumin |
| N/A |
| Side Effects of Albumin |
| 1.Allergic reactions 2.Nausea, Vomiting 3.Increased salivation 4.Fever and chills 5.Vascular overload 6.Haemodilution and Pulmonary oedema |
| Contra-indications of Albumin |
| 1.Cardiac failure 2.Severe anaemia 3.History of hypersensitivity 4.Parenteral nutrition |
| Special Precautions while taking Albumin |
| 1.Heart disease 2.Kidney disease 3.Liver problems 4.Blood disorders 5.Anemia 6.Allergies (especially to protein) |
| Pregnancy Related Information |
| Contraindicated |
| Old Age Related Information |
| Use with caution |
| Breast Feeding Related Information |
| N/A |
| Children Related Information |
| Use with caution |
| Indications for Albumin |
| 1.Acute hypovolaemic shock 2.Hypoproteinaemia 3.Neonatal hyperbilirubinaemia |
| Interactions for Albumin |
| Albumin solution should not be mixed by protein hydrolysates or alcoholic solutions. |
| Typical Dosage for Albumin |
| Acute hypovolaemic shock Adult: Initially, 25 g of albumin, adjusted according to patient’s response. Usual rates of infusion: Up to 5 ml/minute (5% solution) or 1-2 ml/minute (20% solution). Child: Up to 1 g/kg, adjusted according to patient’s response. Usual rates of infusion: Up to 5 ml/minute (5% solution) or 1-2 ml/minute (20% solution). Intravenous Hypoproteinaemia Adult: Up to 2 g/kg daily. Usual rates of infusion: Up to 5 ml/minute (5% solution) or 1-2 ml/minute (20% solution). Intravenous Neonatal hyperbilirubinaemia Child: 1 g/kg of albumin before exchange transfusion. Usual rates of infusion: Up to 5 ml/minute (5% solution) or 1-2 ml/minute (20% solution). |
| Schedule of Albumin |
| H |
| Storage Requirements for Albumin |
| Store in the original container to protect from light. Store below 30?C. Do not freeze. Do not use after expiration date |
| Effects of Missed Dosage of Albumin |
| N/A |
| Effects of Overdose of Albumin |
| N/A |